During use of vascular interventional devices with lubricating coatings, the coating may peel off or partially fall off if the coating is not firmly bonded to the catheter guidewire base material or if the coating is defective in the dry state. Therefore, coating integrity evaluation is an important prerequisite to ensure the safety and effectiveness of relevant coating products. This article describes the use of visual inspection in coating integrity evaluation.
During use of vascular interventional devices with lubricating coatings, the coating may peel off or partially fall off if the coating is not firmly bonded to the catheter guidewire base material or if the coating is defective in the dry state. Therefore, coating integrity evaluation is an important prerequisite to ensure the safety and effectiveness of relevant coating products. This article describes the use of visual inspection in coating integrity evaluation.
During use of vascular interventional devices with lubricating coatings, the coating may peel off or partially fall off if the coating is not firmly bonded to the catheter guidewire base material or if the coating is defective in the dry state. Therefore, coating integrity evaluation is an important prerequisite to ensure the safety and effectiveness of relevant coating products. This article describes the use of visual inspection in coating integrity evaluation.
Insoluble particles in medical devices are non-metabolizable particle impurities that are insoluble in water and invisible to the naked eye. The particle size is generally less than 50 μm. They are difficult to be metabolized in the human body and may cause granulomas, vascular embolism, phlebitis, tumors, pyrogen reactions, etc.
Anticoagulant coatings can effectively reduce the risk of thrombosis on the surface of blood-contact medical devices. In the last issue, we introduced two major types of anti-coagulation coating strategies: 'inert' and 'active'. Since different anticoagulant strategies have different mechanisms of action and anticoagulation, the detection methods for pre-evaluation of anticoagulant performance in vitro are also different.