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Clotclear® 
Heparin Coating
Covalent heparin molecule grafting technology, compatible with various metal and polymer substrates, effectively inhibiting thrombosis on the product surface
Application examples: Vascular stents, flow diverters, valves, ECMO, artificial hearts, CVC, etc.
Product Introduction
The Clotclear® Surface is a self-developed anticoagulant coating by BIOSURF with heparin as the main active component. It is suitable for all kinds of blood-contact medical devices to reduce the risk of thrombus formation on medical device surfaces. The Clotclear® Surface can be applied to a wide range of polymer and metal substrates with the advantages of firmness and bioactivity protection which is based on BIOSURF's unique adhesive layer technology and molecular covalent grafting process.
Product Advantages
  • Good homogeneity and firmness with the technique of molecular covalent grafting.
  • Mild process conditions without high temperatures and strong acids and bases.
  • More conducive to the maintenance of heparin activity by hydrophilic adhesive.
  • Good flexibility and adjustability of the coating thickness and heparin density.
  • Widely suitable for all types of metal and polymer substrates.
  • Good applicability of the coating process for both inner and outer wall without the limitation by the shape of the product.
  • Blood compatibility met the standard of ISO 10993/ GB/T 16886.
  • Professional service support covering the entire product life cycle from R&D to stable mass production
  • Assisting in the establishment of performance evaluation systems and preparation of product registration documents
Applicable Products
Vascular Stents, heart valves, artificial blood vessels, extracorporeal membrane oxygenation (ECMO), hemodialysis, central venous catheters (CVC), etc
Product Performance
  • Coating Appearance
Coating Dyeing: Clotclear® coating can be uniformly applied on various substrates
  • Anticoagulant Performance
PTT Test: Clotclear® coating can effectively prolong coagulation

Tel: (+86) 134 0143 1324
Email: sales@biosurf.cn
Working hours: 08:30-17:30 (Monday - Friday)
Address: Building 26, Dongjing Industrial Park, No. 1 Jintian Road, Suzhou Industrial Park, China

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(+86) 134 0143 1324

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